Receptors & Transporters/G protein coupled receptors/Adenosine/Non-selective Hello Bio Non-selective, competitive adenosine receptor antagonist / PDE inhibitor Hello Bio Shows potential protective actions against dementia and age-related memory decline and anti-cancer actions. Non-selective and competitive adenosine receptor antagonist (Ki values are 27-30 and 50 µM at A2 and A1 receptors respectively). Non-selective Adenosine Tocris Bioscience 2793 Mobilizes calcium from intracellular stores and inhibits benzodiazepine binding to GABA receptors. Antagonist at A1 and A2A adenosine receptors and inhibitor of cyclic nucleotide phosphodiesterases.
Tocris Bioscience 2793Ĭentral nervous system stimulant. Mobilizes calcium from intracellular stores and inhibits benzodiazĮpine binding to GABA receptors. CNS stimulant Tocris Bioscience 2793Īdenosine Receptors Tocris Bioscience 2793īiochemicals & small molecules/Antagonists & inhibitors Hello BioĬaffeine -> 1,3,7-trimethylurate PlantCyc 1-3-7-TRIMETHYLXANTHINEĬaffeine + a demethylated methyl donor -> theophylline + a methylated methyl donor PlantCyc 1-3-7-TRIMETHYLXANTHINEĬentral nervous system stimulant. Bio Activity: 7-TM Receptors Tocris Bioscience 2793Ī1 and A2B antagonist.Theobroma cacao PlantCyc 1-3-7-TRIMETHYLXANTHINE Linum usitatissimum PlantCyc 1-3-7-TRIMETHYLXANTHINE Compound Source: caffeine biosynthesis I PlantCyc 1-3-7-TRIMETHYLXANTHINEĬaffeine biosynthesis II (via paraxanthine) PlantCyc 1-3-7-TRIMETHYLXANTHINEĬaffeine degradation I (main, plants) PlantCyc 1-3-7-TRIMETHYLXANTHINEĬaffeine degradation II PlantCyc 1-3-7-TRIMETHYLXANTHINE.A purine alkaloid that occurs naturally in tea and coffee. Chemical Class: A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7.
#PH DIFFERENT ON CAFFEINE STRUCTURE SKIN#
WARNING: Causes CNS effects, skin and eye irritation Alfa Aesar 39214 OU Chemical Safety Data (No longer updated) More details ORL-RAT LD50 192 mg kg-1, IPR-RAT LD50 260 mg kg-1, IVN-RAT LD50 105 mg kg-1, SCU-RAT LD50 170 mg kg-1 OU Chemical Safety Data (No longer updated) More detailsĭANGER: POISON, irritates skin, eyes, lungs Alfa Aesar 39214, A10431 Toxicity: Organic Compound Amide Drug Food Toxin Central Nervous System Stimulant Anorexigenic Agent Appetite Depressant Phosphodiesterase Inhibitor Metabolite Household Toxin Natural Compound Purinergic P1 Receptor Antagonist Toxin, Toxin-Target Database T3D2712.Incompatible with strong acids, strong bases, strongoxidizing agents, iodine, silver salts, tannins. Appearance: odourless white powder or crystals OU Chemical Safety Data (No longer updated) More details.Experimental Density: 1.23 g/mL Alfa Aesar A10431, 39214.Soluble to 100 mM in water and to 50 mM in DMSO Tocris Bioscience 2793 NaOH, and to 50 mM in DMSO Tocris Bioscience 2793 Soluble to 10 mM in water with sonication, to 100 mM in 1eq. Experimental Solubility: Soluble in pyrrole, THF-H2O mixture, ethyl acetate Alfa Aesar A10431.Experimental Boiling Point: 178 ☌ (Sublimes) Alfa Aesar.Experimental Melting Point: 234-236 ☌ Alfa AesarĢ37 ☌ OU Chemical Safety Data (No longer updated) More detailsĢ37 ☌ Jean-Claude Bradley Open Melting Point Dataset 14937Ģ38 ☌ Jean-Claude Bradley Open Melting Point Dataset 17008, 17229, 22105, 27892, 27893, 27894, 27895Ģ35.25 ☌ Jean-Claude Bradley Open Melting Point Dataset 27892, 27893, 27894, 27895Ģ36 ☌ Jean-Claude Bradley Open Melting Point Dataset 27892, 27893, 27894, 27895Ģ35 ☌ Jean-Claude Bradley Open Melting Point Dataset 6603.Experimental Physico-chemical Properties.Fema No: 2224 Sigma-Aldrich ALDRICH-W222402.
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